Mesut Ozil and Alexis are among four players to be recalled after missing last weekend's FA Cup win over Preston North End.
Petr Cech comes back in goal, behind Laurent Koscielny who returns as captain. Shkodran Mustafi, Nacho Monreal and Gabriel at right-back complete the back four.
Aaron Ramsey and Granit Xhaka continue in midfield with Alex Iwobi keeping his place on the wing.
Elsewhere, Olivier Giroud retains his place up front after scoring a late winner last weekend.
Arsenal: Cech, Gabriel, Koscielny, Mustafi, Monreal, Ramsey, Xhaka, Ozil, Iwobi, Giroud, Alexis.
Subs: Ospina, Lucas, Oxlade-Chamberlain, Holding, Reine-Adelaide, Maitland-Niles, Welbeck.
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