Arsene Wenger has made nine changes to his side for their FA Cup fifth-round tie against Hull City.
Danny Welbeck makes his first start in 10 months after his heroics against Leicester City while David Ospina replaces Petr Cech in goal.
Under-21s goalkeeper Matt Macey is named on the bench and is joined by Olivier Giroud and Alexis.
Arsenal: Ospina, Chambers, Koscielny, Mertesacker, Gibbs, Flamini, Elneny, Campbell, Iwobi, Welbeck, Walcott
Arsenal substitues: Macey, Bellerin, Monreal, Coquelin, Oxlade-Chamberlain, Alexis, Giroud
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