Danny Welbeck is named on the bench for the first time this season, having not played for 10 months following knee surgery.
Arsene Wenger has made two changes to his starting XI, as Per Mertesacker replaces Gabriel in defence, while Francis Coquelin starts in midfield alongside Aaron Ramsey.
Alex Oxlade-Chamberlain makes his 100th Premier League appearance for the Gunners and new signing Mohamed Elneny is among the substitutes.
Arsenal: Cech, Bellerin, Mertesacker, Koscielny, Monreal ,Coquelin, Ramsey, Oxlade-Chamberlain, Ozil, Alexis, Giroud
Arsenal substitutes: Ospina, Chambers, Flamini, Elneny, Campbell, Walcott, Welbeck
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