Arsene Wenger has made four changes to the side that beat Middlesbrough 2-0 in the FA Cup.
David Ospina comes back in for Wojciech Szczesny, Per Mertesacker returns to captain the side at the expense of Gabriel, while Nacho Monreal and Francis Coquelin replace Kieran Gibbs and Mathieu Flamini.
Elsewhere, Jack Wilshere returns from injury to start the game on the bench.
Full team: Ospina, Chambers, Mertesacker, Koscielny, Monreal, Coquelin, Cazorla, Welbeck, Ozil, Alexis, Giroud
Substitutes: Szczesny, Gibbs, Bellerin, Gabriel, Wilshere, Rosicky, Walcott
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