Arsene Wenger has made three changes to the side that lost against Borussia Dortmund on Tuesday night.
Calum Chambers replaces Hector Bellerin at right-back while Santi Cazorla comes in for Jack Wilshere in midfield and Alex Oxlade-Chamberlain takes Alexis Sanchez's place.
Elsewhere, Danny Welbeck continues up front.
Team in full to play Aston Villa: Szczesny, Chambers, Mertesacker, Koscielny, Gibbs, Arteta, Ramsey, Cazorla, Ozil, Oxlade-Chamberlain, Welbeck
Substitutes: Ospina, Coquelin, Diaby, Alexis, Rosicky, Wilshere, Podolski
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