Arsene Wenger has made five changes to the side that beat Brighton & Hove Albion 3-2 in the FA Cup on Sunday.
David Ospina returns in place of Wojciech Szczesny while Per Mertesacker and Hector Bellerin replace Kieran Gibbs and Calum Chambers.
Elsewhere, Francis Coquelin comes in for Mathieu Flamini and Santi Cazorla replaces Tomas Rosicky.
New signing Gabriel starts the game on the bench.
Full team: Ospina, Bellerin, Mertesacker, Koscielny, Monreal, Coquelin, Ramsey, Walcott, Cazorla, Ozil, Giroud
Substitutes: Szczesny, Gibbs, Gabriel, Chambers, Flamini, Rosicky, Akpom
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