Arsene Wenger has made three changes to the side that lost against Chelsea.
Hector Bellerin comes in for the suspended Calum Chambers while Nacho Monreal and Alex Oxlade-Chamberlain replace Laurent Koscielny and Mesut Ozil.
Santi Cazorla, Alexis Sanchez and Danny Welbeck retain their places in attack.
Full team as follows:
Starting lineup: Szczesny, Bellerin, Mertesacker, Monreal, Gibbs, Flamini, Wilshere, Oxlade-Chamberlain, Cazorla, Alexis, Welbeck
Substitutes: Martinez, Ajayi, Coquelin, Arteta, Rosicky, Ramsey, Campbell