Mikel Arteta has made five changes to his side for tonight’s game at PSV Eindhoven, with Aaron Ramsdale getting a start in goal and Gabriel Martinelli set to make his 100th appearance for the club.
The shot-stopper keeps his place between the post for his first ever taste of Europan football, with Matt Turner struggling with a tight groin.
In defence, Kieran Tierney and Rob Holding replace Ben White and Gabriel in the back four, and Sambi Lokonga comes in for Thomas Partey in midfield.
In attack, Eddie Nketiah and Fabio Vieira are preferred to Gabriel Jesus and Bukayo Saka. Meanwhile, Martinelli will complete his century of Gunners games - more on his achievement.
PSV meanwhile have made three changes to the side that lost 4-2 to Groningen on Sunday.
Two are in defence with Phillipp Mwene and Jarrad Branthwaite replacing Jordan Teze and Armando Obispo, while Guus Til comes out of attack for the fit again Erick Gutierrez.
PSV: Benitez, Mwene, Ramalho, Branthwaite, Max, Veerman, Sangare, Gutierrez, Xavi Simons, Gakpo, El Ghazi. Subs: Drommel, Waterman, Hoever, Teze, Obispo, Van Ginkel, De Jong, Madueke, Mauro Junior, Til, Bakayoko, Ledezma.
Arsenal: Ramsdale, Tomiyasu, Saliba, Holding, Tierney, Lokonga, Xhaka, Vieira, Odegaard, Martinelli, Nketiah. Subs: Hein, White, Cedric, Gabriel, Partey, Smith, Cirjan, Ibrahim, Nelson, Saka, Jesus.
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