Aaron Ramsey will start the north London derby against Tottenham.
The Wales midfielder replaces Abou Diaby, who has been ruled out with a calf injury.
Ramsey is the solitary change from the side that started against Aston Villa last weekend.
Lukas Podolski and Alex Oxlade-Chamberlain are among the substitutes.
Arsenal team: Szczesny, Jenkinson, Mertesacker, Vermaelen, Monreal, Ramsey, Arteta, Wilshere, Cazorla, Walcott, Giroud; Subs: Koscielny, Rosicky, Podolski, Oxlade-Chamberlain, Coquelin, Mannone, Gervinho
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