Sebastien Squillaci will make his Arsenal debut against Bolton at Emirates Stadium today.
Emmanuel Eboue and Kieran Gibbs also start as Bacary Sagna and Gael Clichy drop to the bench.
Marouane Chamakh starts up-front in the absence of injured pair Robin van Persie and Theo Walcott.
Cesc Fabregas captains the side that also includes Tomas Rosicky. The returning Samir Nasri makes the bench.
Arsenal team in full: Almunia, Eboue, Squillaci, Koscielny, Gibbs, Wilshere, Fabregas, Rosicky, Song, Chamakh, Arshavin
Substitutes: Fabianski, Clichy, Denilson, Sagna, Nasri, Vela, Diaby