Carl Jenkinson will make his third start of the Premier League campaign when Sunderland visit Emirates Stadium on Sunday.
The 19-year-old takes the place of the injured Bacary Sagna, who has been ruled out for a minimum of three months after suffering a fractured fibula in his right ankle.
Meanwhile Laurent Koscielny returns at the heart of defence after his injury, signalling a return to midfield for utility man Alex Song.
Team in full: Szczesny, Jenkinson, Mertesacker, Koscielny, Gibbs, Song, Arteta, Rosicky, Walcott, Gervinho, Van Persie.
Substitutes: Fabianski, Andre Santos, Djourou, Frimpong, Arshavin, Benayoun, Park.Copyright 2016 The Arsenal Football Club plc. Permission to use quotations from this article is granted subject to appropriate credit being given to www.arsenal.com as the source