By Nick Teale
Lukasz Fabianski starts in goal against Wigan and defender Sol Campbell has been handed the captain's armband by Arsène Wenger.
The manager has made a total of four changes from the team that lost to Tottenham on Wednesday night.
Thomas Vermaelen limped off during the North London with a calf strain and so misses today's game.
Conor Henderson is included on the bench. The 18-year-old midfielder is a Republic of Ireland youth international and could make his Premier League debut today.
Arsenal team in full: Fabianski, Sagna, Campbell, Silvestre, Clichy, Diaby, Rosicky, Eastmond, Nasri, Walcott, Bendtner
Substitutes: Mannone, Traore, Eboue, Merida, Henderson, Vela, Van Persie