The duo started in the midweek victory at West Brom in the Carling Cup. It represented the first competitive game of the season for Senderos while injury has also restricted Flamini's involvement this term.
"We lost Emmanuel Adebayor on Tuesday night but he has recovered very well and he may be ready for Moscow," said Arsène Wenger. "I will rotate the squad a bit on Saturday. Senderos and Flamini will be back and Aliadiere stays in.
"Gael Clichy is not involved because I want him to work hard but he is very close now. I feel he is not completely ready because there are still little compensations. He has been out for so long and I do not want to rush him back now and get him injured again. He is a precious jewel - a left back - and we do not have many."
"I thought Eboue would be available for Everton," said Wenger. "But it will be a little bit longer than expected. I don't think he will be available for Moscow but he has a little chance for West Ham but a very good one for Everton [in the Carling Cup]. Baptista will be two more weeks at least."