Giroud and Podolski both add new dimensions to the front line, while Cazorla has all the potential to become a midfield general of the highest order.
The trio all have proven their worth on the big stage, and that makes the 20/1 on offer for Arsenal winning the Champions League look tempting.
The Gunners have also won the FA Cup on 11 occasions and are 8/1 to lift the coveted trophy yet again.
Arsenal were unlucky in the League Cup quarter-finals last year when pushing a strong Manchester City side all the way, only to be undone seven minutes from time by Sergio Aguero's breakaway goal. GunnersGaming make them 9/1 to win the competition for a third time, having previously been successful in 1987 and 1993.
You can also get 74/1 for a Premier League and FA Cup double.
Other interesting bets on offer are 2/5 for Arsenal to finish ahead of Tottenham, and 3/2 for an undefeated August. You can back Giroud for top goalscorer at 11/5 or Germany international Podolski at 16/5.
Finally, if you fancy new-look Arsenal to get off to a flying start they are 37/2 with GunnersGaming to be unbeaten in the first 10 league games.
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*Odds correct at time of writing. Terms and conditions apply.