Arsène Wenger has explained the major absences in his squad for the trip to FC Twente on Wednesday.

Arsenal are missing five major names and the long-term sidelined Tomas Rosicky and Eduardo.

It leaves the Frenchman relying on youngsters like Aaron Ramsey and Denilson to inspire his squad to a crucial victory in Holland.

"We have a big squad at home" said Wenger.

"Kolo Toure, Philippe Senderos, Cesc Fabregas, Samir Nasri, Abou Diaby, Tomas Rosicky and Eduardo are out.

"Kolo has a hip muscle problem. Cesc has a hamstring problem, he will be out for the next two games.

"Abou Diaby (thigh) will be out for a while, we knew that. Philippe Senderos has a scan on his hamstring. He did that today whereas Fabregas did his hamstring yesterday.

"Samir Nasri (knee/thigh) should be OK for Saturday and so should Kolo Toure".

When asked who was likely to come in as a replacement the manager replied "Aaron Ramsey has a good chance to start".

Arsenal squad
Manuel ALMUNIA
Lukasz FABIANSKI
Bacary SAGNA
William GALLAS
Gael CLICHY
Justin HOYTE
Johan DJOUROU
Aaron RAMSEY
Jack WILSHERE
Kieran GIBBS
DENILSON
Theo WALCOTT
Emmanuel EBOUE
Mark RANDALL
Emmanuel ADEBAYOR
Robin VAN PERSIE
Nicklas BENDTNER
Carlos VELA

Copyright 2014 The Arsenal Football Club plc. Permission to use quotations from this article is granted subject to appropriate credit being given to www.arsenal.com as the source 12 Aug 2008