Arsène Wenger's side have started the season well, and The Football Predictor suggests they have a 63 per cent chance of coming out on top on Saturday.
The Gunners are currently fifth in the Premier League, and were impressive in their 1-1 draw away at Manchester City last weekend.
The Predictor reveals that they have failed to score in just 10 per cent of their last 20 home games, while Chelsea have not found the net in 30 per cent of their away matches in the same period.
Arsenal have opened the scoring in 65 per cent of their last 20 games on their own patch, and are 10/13 to do so against Chelsea.
The last 20 matches at Emirates Stadium have produced an average of 3.1 goals a game, and GunnersGaming have priced over 2.5 goals being scored on Saturday at 13/15.
The Predictor reveals that 53 per cent of the 45 goals scored at home in the last 20 games have come from forwards, with midfielders netting 29 per cent.
Podolski has already scored three goals for Arsenal and is priced up at 5/1 to net first against Chelsea.
Meanwhile, Cazorla has looked a real threat in front of goal all season and can be backed at 8/1 to break the deadlock.
*Odds correct at time of writing. Terms and conditions apply.29 Sep 2012