Arsenal are unchanged from the side that beat Liverpool 4-1 at Emirates Stadium on Saturday.
Laurent Koscielny has shrugged off a thigh concern to start at Turf Moor alongside Per Mertesacker while Hector Bellerin continues his run in the first team.
Elsewhere, Santi Cazorla partners Francis Coquelin in midfield while Olivier Giroud will be looking to add to his 14 Premier League goals up front.
Full team: Ospina, Bellerin, Mertesacker, Monreal, Coquelin, Cazorla, Ramsey, Ozil, Alexis, Giroud
Subs: Szczesny, Gibbs, Chambers, Flamini, Rosicky, Walcott, Welbeck
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