Arsenal, who secured the title last weekend, ended their campaign with a 4-1 win against Birmingham City.
Little's tremendous goal-filled season ended with her 22nd in the league and her 47th in all competitions.
First-half strikes by Lauren Bruton and Jennifer Beattie set the Gunners up for a comfortable victory over the third-bottom team.
Little added the third goal seven minutes after the interval and captain Jayne Ludlow bagged the fourth four minutes from time.
Substitute Gina Goulding hit a last-minute consolation effort, but Birmingham's season limped to a sad end with their sixth defeat in seven outings.
- Bruton 79 Goal!
- Beattie 45 Goal!
- Ludlow Goal!
- Little Goal!
- Carter 54 45
- Fay 79
- Lander 54
Birmingham City Ladies
- Goulding Goal!